Nurse-Family Partnership (NFP)®

Model effectiveness research report last updated: 2019

Effects shown in research

Reductions in child maltreatment

Findings rated high

Eckenrode, J., Zielinski, D., Smith, E., Marcynyszyn, L. A., Henderson, C. R., Kitzman, H., et al. (2001). Child maltreatment and the early onset of problem behaviors: Can a program of nurse home visitation break the link? Development and Psychopathology, 13(4), 873–890.

Nurse-Family Partnership (NFP)^®

Show findings details

Outcome measure	Effect	Follow-up timing	Sample	Sample size	Intervention group	Comparison group	Group difference	Effect size	Statistical significance	Notes
Percentage abused	FavorableUnfavorable or ambiguousNo Effect	15-year follow-up	Nurse visited during pregnancy + infancy and comparison (Elmira)	228 adolescents	= 0.39	= 0.37	Mean difference = 2.00	Not available	Statistical significance not reported	footnote5 Submitted by user on Fri, 03/15/2019 - 14:29 Information on sample sizes for this study was received through communication with the authors. HomVEE previously rated 24-month outcomes for nurse home visitors Moderate due to high attrition. Upon further examination, HomVEE noted that the outcomes had low attrition, and therefore they rate High.
Percentage neglected	FavorableUnfavorable or ambiguousNo Effect	15-year follow-up	Nurse visited during pregnancy + infancy and comparison (Elmira)	228 adolescents	= 0.61	= 0.63	Mean difference = -2.00	Not available	Statistical significance not reported	footnote5 Submitted by user on Fri, 03/15/2019 - 14:29 Information on sample sizes for this study was received through communication with the authors. HomVEE previously rated 24-month outcomes for nurse home visitors Moderate due to high attrition. Upon further examination, HomVEE noted that the outcomes had low attrition, and therefore they rate High.

Kitzman, H., Olds, D. L., Henderson, C. R., Hanks, C., Cole, R., Tatelbaum, R., et al. (1997). Effect of prenatal and infancy home visitation by nurses on pregnancy outcomes, childhood injuries, and repeated childbearing. A randomized controlled trial. JAMA: The Journal of the American Medical Association, 278(8), 644–652.

Nurse-Family Partnership (NFP)^®

Show findings details

Outcome measure	Effect	Follow-up timing	Sample	Sample size	Intervention group	Comparison group	Group difference	Effect size	Statistical significance	Notes
Number of days hospitalized–injuries/ingestions	FavorableUnfavorable or ambiguousNo Effect	2 years postnatal	Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis)	671 children	Adjusted mean = 0.04	Adjusted mean = 0.18	Mean difference = -0.14	Not available	Statistically significant, p < 0.01	footnote1 Submitted by user on Fri, 03/15/2019 - 14:29 Statistical significance reported on authors’ calculations of the log-incidence difference.
Number of emergency department visits–injuries/ingestions	FavorableUnfavorable or ambiguousNo Effect	2 years postnatal	Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis)	671 children	Adjusted mean = 0.33	Adjusted mean = 0.34	Mean difference = -0.01	Not available	Not statistically significant, p > 0.05	footnote1 Submitted by user on Fri, 03/15/2019 - 14:29 Statistical significance reported on authors’ calculations of the log-incidence difference.
Number of hospitalizations–injuries/ingestions	FavorableUnfavorable or ambiguousNo Effect	2 years postnatal	Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis)	671 children	Adjusted mean = 0.01	Adjusted mean = 0.03	Mean difference = -0.02	Not available	Not statistically significant, p > 0.05	footnote1 Submitted by user on Fri, 03/15/2019 - 14:29 Statistical significance reported on authors’ calculations of the log-incidence difference.
Number of outpatient visits–injuries/ingestions	FavorableUnfavorable or ambiguousNo Effect	2 years postnatal	Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis)	671 children	Adjusted mean = 0.11	Adjusted mean = 0.20	Mean difference = -0.09	Not available	Statistically significant, p ≤ 0.05	footnote1 Submitted by user on Fri, 03/15/2019 - 14:29 Statistical significance reported on authors’ calculations of the log-incidence difference.
Total number of health care encounters–injuries/ingestions	FavorableUnfavorable or ambiguousNo Effect	2 years postnatal	Nurse visited during pregnancy + infancy and developmental screening comparison (Memphis)	671 children	Adjusted mean = 0.43	Adjusted mean = 0.56	Mean difference = -0.13	Not available	Statistically significant, p ≤ 0.05	footnote1 Submitted by user on Fri, 03/15/2019 - 14:29 Statistical significance reported on authors’ calculations of the log-incidence difference.

Olds, D. L., Eckenrode, J., Henderson, C. R., Kitzman, H., Powers, J., Cole, R., et al. (1997). Long-term effects of home visitation on maternal life course and child abuse and neglect. Fifteen-year follow-up of a randomized trial. JAMA: The Journal of the American Medical Association, 278(8), 637–643.

Nurse-Family Partnership (NFP)^®

Show findings details

Outcome measure	Effect	Follow-up timing	Sample	Sample size	Intervention group	Comparison group	Group difference	Effect size	Statistical significance	Notes
Substantiated reports of child abuse and neglect (incidence)	FavorableUnfavorable or ambiguousNo Effect	15-year follow-up	Nurse visited during pregnancy and comparison (Elmira)	227 mothers	Adjusted mean = 0.35	Adjusted mean = 0.54	Mean difference = -0.19	Not available	Statistical significance not reported
Substantiated reports of child abuse and neglect (incidence)	FavorableUnfavorable or ambiguousNo Effect	15-year follow-up	Nurse visited during pregnancy + infancy and comparison (Elmira)	245 mothers	Adjusted mean = 0.29	Adjusted mean = 0.54	Mean difference = -0.25	Not available	Statistically significant, p < 0.01	footnote1 Submitted by user on Fri, 03/15/2019 - 14:29 Statistical significance reported on authors’ calculations of the log-incidence difference.

Olds, D. L., Henderson Jr., C. R., Chamberlin, R., & Tatelbaum, R. (1986). Preventing child abuse and neglect: A randomized trial of nurse home visitation. Pediatrics, 78, 65–78.

Nurse-Family Partnership (NFP)^®

Show findings details

Outcome measure	Effect	Follow-up timing	Sample	Sample size	Intervention group	Comparison group	Group difference	Effect size	Statistical significance
Number of emergency room visits for accidents and poisonings (first year of life)	FavorableUnfavorable or ambiguousNo Effect	1-year follow-up	Nurse visited during pregnancy and comparison (Elmira)	205 children	Adjusted mean = 0.12	Adjusted mean = 0.06	Mean difference = 0.06	Not available	Statistical significance not reported
Number of emergency room visits for accidents and poisonings (first year of life)	FavorableUnfavorable or ambiguousNo Effect	1-year follow-up	Nurse visited during pregnancy + infancy and comparison (Elmira)	223 children	Adjusted mean = 0.12	Adjusted mean = 0.06	Mean difference = 0.06	Not available	Not statistically significant, p > 0.05
Number of emergency room visits for accidents and poisonings (second year of life)	FavorableUnfavorable or ambiguousNo Effect	2-year follow-up	Nurse visited during pregnancy + infancy and comparison (Elmira)	196 children	Adjusted mean = 0.15	Adjusted mean = 0.34	Mean difference = -0.19	Not available	Statistically significant, p < 0.05
Number of emergency room visits for accidents and poisonings (second year of life)	FavorableUnfavorable or ambiguousNo Effect	2-year follow-up	Nurse visited during pregnancy and comparison (Elmira)	185 children	Adjusted mean = 0.32	Adjusted mean = 0.34	Mean difference = -0.02	Not available	Statistical significance not reported
Substantiated abuse or neglect	FavorableUnfavorable or ambiguousNo Effect	2-year follow-up	Nurse visited during pregnancy and comparison	247 children	% (adjusted) = 8.00	Adjusted mean % = 10.00	Mean difference = -2.00	HomVEE calculated = -0.15	Not statistically significant, p > 0.10
Substantiated abuse or neglect	FavorableUnfavorable or ambiguousNo Effect	2-year follow-up	Nurse visited during pregnancy + infancy and comparison	256 children	% (adjusted) = 5.00	Adjusted mean % = 10.00	Mean difference = -5.00	HomVEE calculated = -0.45	Not statistically significant, p > 0.10

Olds, D. L., Henderson, C. R., & Kitzman, H. (1994). Does prenatal and infancy nurse home visitation have enduring effects on qualities of parental caregiving and child health at 25 to 50 months of life? Pediatrics, 93(1), 89–98.

Nurse-Family Partnership (NFP)^®

Show findings details

Outcome measure	Effect	Follow-up timing	Sample	Sample size	Intervention group	Comparison group	Group difference	Effect size	Statistical significance	Notes
New substantiated cases of abuse/neglect from 25 to 48 months	FavorableUnfavorable or ambiguousNo Effect	48 months	Nurse visited during pregnancy and comparison (Elmira)	245 children	% (adjusted) = 4.00	Adjusted mean % = 5.00	Mean difference = -1.00	HomVEE calculated = -0.14	Statistical significance not reported
New substantiated cases of abuse/neglect from 25 to 48 months	FavorableUnfavorable or ambiguousNo Effect	48 months	Nurse visited during pregnancy + infancy and comparison (Elmira)	253 children	% (adjusted) = 8.00	Adjusted mean % = 5.00	OR = 1.80	Study reported = 0.30	Not statistically significant p > 0.05	footnote7 Submitted by user on Fri, 03/15/2019 - 14:29 The <abbr title="Home Visiting Evidence of Effectiveness">HomVEE</abbr> reversed the odds ratio from the study-reported calculation to reflect the odds of the treatment versus the control group.
Number of emergency department visits for injuries/ingestions (25 to 50 months)	FavorableUnfavorable or ambiguousNo Effect	50 months	Nurse visited during pregnancy + infancy and comparison (Elmira)	221 children	Adjusted mean = 0.47	Adjusted mean = 0.61	Mean difference = -0.14	Not available	Not statistically significant, p > 0.05	footnote1 Submitted by user on Fri, 03/15/2019 - 14:29 Statistical significance reported on authors’ calculations of the log-incidence difference.
Number of injuries/ingestions in physician record (25 to 50 months)	FavorableUnfavorable or ambiguousNo Effect	50 months	Nurse visited during pregnancy + infancy and comparison (Elmira)	221 children	Adjusted mean = 0.34	Adjusted mean = 0.57	Mean difference = -0.23	Not available	Statistically significant, p ≤ 0.05	footnote1 Submitted by user on Fri, 03/15/2019 - 14:29 Statistical significance reported on authors’ calculations of the log-incidence difference.

Olds, D. L., Kitzman, H. J., Cole, R. E., Hanks, C. A., Arcoleo, K. J., Anson, E. A., Luckey, D. W., Knudtson, M. D., Henderson, C. R., Bondy, J., & Stevenson, A. J. (2010). Enduring effects of prenatal and infancy home visiting by nurses on maternal life course and government spending: Follow-up of a randomized trial among children at age 12 years. Archives of Pediatrics & Adolescent Medicine, 164(5), 419-424

Nurse-Family Partnership (NFP)^®

Show findings details

Outcome measure	Effect	Follow-up timing	Sample	Sample size	Intervention group	Comparison group	Group difference	Effect size	Statistical significance
Child foster care placements	FavorableUnfavorable or ambiguousNo Effect	0 to 12 years	Nurse visited during pregnancy and infancy and development screening comparison (Memphis)	594 mothers	%(adjusted) = 12.00	Adjusted mean % = 4.00	OR = 3.33	HomVEE calculated = 0.72	Not statistically significant, p ≥ 0.05

Zielinski, D. S., Eckenrode, J., & Olds, D. L. (2009). Nurse home visitation and the prevention of child maltreatment: Impact on the timing of official reports. Development and Psychopathology, 21(2), 441–453. doi:10.1017/S0954579409000248

Nurse-Family Partnership (NFP)^®

Show findings details

Outcome measure	Effect	Follow-up timing	Sample	Sample size	Intervention group	Comparison group	Group difference	Effect size	Statistical significance
Number maltreatment, substantiated reports (percentage)	FavorableUnfavorable or ambiguousNo Effect	15-year follow-up	Nurse visited during pregnancy + infancy and comparison (Elmira)	Unknown	= 0.76	= 0.68	= 8.00	HomVEE calculated = 0.24	Statistical significance not reported
Number neglect, substantiated reports (percentage)	FavorableUnfavorable or ambiguousNo Effect	15-year follow-up	Nurse visited during pregnancy + infancy and comparison (Elmira)	Unknown	= 0.83	= 0.73	= 10.00	HomVEE calculated = 0.36	Statistical significance not reported
Onset of maltreatment	FavorableUnfavorable or ambiguousNo Effect	15-year follow-up	Nurse visited during pregnancy + infancy and comparison (Elmira)	Unknown	Not available	Not available	HR = 0.73	Not available	Statistical significance not reported
Onset of neglect	FavorableUnfavorable or ambiguousNo Effect	15-year follow-up	Nurse visited during pregnancy + infancy and comparison (Elmira)	Unknown	Not available	Not available	HR = 0.59	Not available	Statistical significance not reported

Findings rated moderate

Olds, D. L., Henderson, C. R., & Kitzman, H. (1994). Does prenatal and infancy nurse home visitation have enduring effects on qualities of parental caregiving and child health at 25 to 50 months of life? Pediatrics, 93(1), 89–98.

Nurse-Family Partnership (NFP)^®

Show findings details

Outcome measure	Effect	Follow-up timing	Sample	Sample size	Intervention group	Comparison group	Group difference	Effect size	Statistical significance
Number of emergency department visits for injuries/ingestions (25 to 50 months)	FavorableUnfavorable or ambiguousNo Effect	50 months	Nurse visited during pregnancy and comparison (Elmira)	209 children	Adjusted mean = 0.46	Adjusted mean = 0.61	Mean difference = -0.15	Not available	Statistical significance not reported
Number of injuries/ingestions in physician record (25 to 50 months)	FavorableUnfavorable or ambiguousNo Effect	50 months	Nurse visited during pregnancy and comparison (Elmira)	209 children	Adjusted mean = 0.56	Adjusted mean = 0.57	Mean difference = -0.01	Not available	Statistical significance not reported

View Revisions